经蝶窦显微手术治疗垂体侵袭性腺瘤

Transsphenoidal microscopic removal of invading pituitry adenoma

为总结临床经验，报告经蝶窦进路显微手术治疗垂体侵袭性腺瘤１８例，其中４例伴有胰岛素依赖型糖尿病。施肿瘤近全切除１５例，大部分切除３例。术后追加放射治疗１０例，服用溴隐亭治疗５例。术后平均随访３．８年，其中３例（１６．６％）平均１．６年复发，二次经额手术治愈。就垂体侵袭性腺瘤和伴有胰岛素依赖型糖尿病患者经蝶窦显微手术治疗的可行性进行探讨。

Eighteen cases of invading pituitary adenoma were removed via the approach of transsphenoidal microscopical operation. Among them 4 cases had insulin dependent diabetes.The pituitary adenoma were near totally removed in 15 cases,partially removed in 3,and 10 cases were treated by supplement radiotherapy postoperatively and 5 cases by oral bromocriptin postoperatively.The average time of follow up was 3.8 years.There were 3 cases(16.6%) had postoperative recurrence of the tumor which were finally cured by transfrontal craniotomy.The feasibility of the transsphenoidal microscopic approach for the invading pituitaty adenoma was discussed.