摘要
目的:为寻找治疗真性红细胞增多症(polycythemiavera,PV)的有效方法。方法:应用活(破)血逐瘀法治疗28例PV患者。结果:其中4例临床缓解,11例好转,总有效率达53.6%。活(破)血逐瘀法治疗有效者骨髓中红细胞生成素依赖性红系祖细胞(EPO+CFU-E)及红细胞生成素非依赖性红系祖细胞(EPO-CFU-E)均明显减少,尤以后者更为显著。结论:本疗法主要通过作用于EPO-CFU-E而发挥疗效;此外,活(破)血逐瘀治疗有效者骨髓成纤维样祖细胞(CFU-F)数量亦有明显变化。
To assess the efficacy of 'method of activationg blood circulation and removing stasis (ABCRS)' in treating polycythemia vera. Methods: 28 cases of polycythemia vera were treated with ABCRS and observed with bone marrow colonies. Results: 15 oasses were responsibe, of them 4 cases reached clinical remission, 11 cases were improved. Both bone marrow colonies of colony forming unit-erythroid dependent of erythropoietin (EPO+CFU-E)and colonies of CFU-E independent of EPO (EPO-CFU-E) from these cases decreased significantly especially the latter. ABCRS mainly suppressed the proliferation and differentiation of EPO-CFU-E. In addition, bone marrow colonies of colony formng unit-fibroblastoids (CFU-F) from these cases also changed obviously. Conclusion: ABCRS iseffective in treating polycythemia vera.
出处
《中国中西医结合杂志》
CAS
CSCD
北大核心
1997年第1期20-22,共3页
Chinese Journal of Integrated Traditional and Western Medicine
关键词
真性
红细胞增多症
活血逐瘀法
中医药疗法
polycythemia vera
method of activating blood circulation and removing stasis
colony-form--ing unit-erythroid
erythropoietin
colony-forming unit-fibroblastoid