尿促性素第三批国家标准品的标定

Assay of the Third Batch of National Reference Standard of Menotropins

目的:制备和标定第三批尿促性素国家标准品。方法:用幼龄大鼠卵巢、精囊增重方法,第四批人尿FSH、LH国际标准品为标准标定第三批尿促性素国家待标品。结果:第三批尿促性素国家标准品的生物效价分别为FSH190IU,LH242IU/支。结论:已成功研制第三批尿促性素国家标准品,可以取代第二批绝经期尿促性素国家标准品,现已分发使用。

Objective：Prepare and assay the third batch of national reference standard of menotropins. Method ：Assay the biological potency of Menotropins in terms of ovary and seminal vesicle weight of impuberism rat,as well as regarded the fourth human FSH,LH as standard. Result：The biological potency of the third batch of national menotropins standard was 190IU/ ampoule（FSH）and 242IU/ampoule（LH）. Conclusion：The preparation of the third batch of national menotropins standard has been substituted the second batch of national menopause menotropins standard successfully and in use.