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胚胎干细胞向心肌细胞方向诱导分化的进展 被引量：2

Induction and Differentiation of Embryonic Stem Cells into Cardiomyocytes
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摘要 胚胎干细胞是具有在体外无限扩增且可向外、中、内三胚层分化的全能干细胞。在体外可以通过自主分化、加入药物、加入生理活性物质、共培养以及转基因等方法对其进行诱导和调节生成心肌细胞,为心肌梗死等心脏重大疾病患者实施细胞治疗提供理想的种子细胞。 Embryonic stem cells （ ESCs ） are total potent stem cells, which have properties of prolonged multiplepropagation in vitro, can differentiate into ectoderm, mesoderm and endoderm. There are kinds of inducible approaches, including spontaneously contracting, adding drugs , adding physiological active compounds, co-culture and transgenic, which can induce and modulate ESC to differentiate into cardiomyocytes in vitro. Induction and differentiation of ESCs towards cardiomyocytes will provides a cell therapy method for myocardial infarction and the other severe cardiopathy.
作者 董韬 刘慧雯 鲍君红
机构地区 哈尔滨医科大学组织学与胚胎学教研室
出处 《解剖科学进展》 CAS 2007年第3期279-282,共4页 Progress of Anatomical Sciences
关键词 胚胎干细胞 成心肌细胞 诱导分化 生理活性物质 全能干细胞 种子细胞 细胞治疗 疾病患者
分类号 R329.2 [医药卫生—人体解剖和组织胚胎学]
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参考文献23

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二级参考文献49

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共引文献49

同被引文献19

  • 1Dan-yanZHU Yi-jiaLOU.Inducible effects of icariin,icaritin,and desmethylicaritin on directional differentiation of embryonic stem cells into cardiomyocytes in vitro[J].Acta Pharmacologica Sinica,2005,26(4):477-485. 被引量：30
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引证文献2

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解剖科学进展
2007年 第3期

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