白癜风免疫学研究进展

Advances in the research about vitiligo immunology

白癜风相关的免疫学研究已成为热点,包括表皮细胞因子表达的失衡和细胞因子网络对黑素细胞的调节;细胞免疫在白癜风发病机制中的作用及特异性T细胞受体识别抗原的分子和功能基础;白癜风的发病与其他自身免疫性疾病的关系;凋亡在黑素细胞破坏过程中的作用等。就白癜风相关的免疫学发病机制进展进行综述。

The immunology of vitiligo has become a hot spot of researches in recent years. These researches mainly focus on the imbalance of epidermal cytokines, regulation of melanocytes by cytokine network, the role of cellular immunity in immune pathogenesis of vitiligo, the molecular and functional bases of antigen recognition by specific T cell receptor, the association of vitiligu occurrence with other autoimmue diseases, effect of apoptosis on the destruction of melanocytes. This paper reviews the advances in the researches related to the immunologic pathogenesis of vitiligo.