增强型磷酸钙骨水泥复合材料添加成分的研究现状

Research of enforced calcium phosphate cement composite

目的:总结并分析增强磷酸钙骨水泥复合材料的技术路线及其影响因素,为临床应用提供理论依据。资料来源:应用计算机检索EI Compendex Web1995-01/2006-12关于增强型磷酸钙骨水泥的文章。检索词"calcium phosphate cement,enforced"并限定文章的语言种类为English。同时利用计算机检索中国期刊全文数据1995-01/2006-12的相关文章,限定文章语言种类为中文,检索词"磷酸钙骨水泥,增强"。资料选择:对资料进行初审,纳入标准:采用复合方法使磷酸钙骨水泥增强。资料提炼:共收集到符合上述要求的文献46篇,排除14篇重复性研究。32篇符合纳入标准。资料综合:磷酸钙骨水泥的复合增强方法主要有添加无机离子、与纤维复合、与大分子物质及有机生物活性物质复合、加入晶须及无机陶瓷颗粒以及同时添加多种组分协同增强。结论:随着对磷酸钙骨水泥复合材料的深入研究,其机械性能以及其他生物性能必将不断提高与完善,以满足临床需要。

OBJECTIVE： To summarize and analyze the technique and influential factors to improve the strength of calcium phosphate cement （CPC） composite, so as to provide theoretical evidence for its clinical application. DATA SOURCES： The relevant articles dated between January 1995 and December 2006 were searched in El Compendex Web with the keywords of ＂calcium phosphate cement, enforced＂. Meanwhile, we searched China Journal Full-text Database for relevant articles published between January 1995 and December 2006 with the same keywords in Chinese. STUDY SELECTION： The data were selected primarily, and the articles that involved the enforcement of calcium phosphate cement by combined methods were selected. DATA EXTRACTION： Totally 46 literatures in accordance with the criteria were collected, and 14 repetitive studies were excluded, 32 were selected. DATA SYNTHESIS： The main methods of enforcing calcium phosphate cement refer to the incorporation of inorganic ions, fibers, macromolecule or organic bioactive substances, whiskers or ceramic particles and various compositions. CONCLUSION： With the further study on calcium phosphate cement composite, its mechanical property and other biological properties must be improved and perfected to meet the clinical requirements.