血液透析患者低蛋白与超敏C反应蛋白、颈动脉内膜-中层厚度关系

The Study on Relation Between Hypoproteinemia and Hs-CRP and IMT in Patients with Hemodialys

目的探讨血液透析患者在不同清蛋白水平下透析后超敏C反应蛋白与颈动脉内膜-中层厚度的关系。方法选择血液透析病人55例,按照透析前血清清蛋白(ALB)水平随机分为3组,并设健康对照组,观测3组病人在透析后超敏C反应蛋白、颈动脉内膜-中层厚度的变化,并探讨两者的关系。结果随着清蛋白水平降低,超敏C反应蛋白依次升高,颈动脉内膜-中层厚度和斑块阳性率都依次增加,两者呈现出明显的相关关系。结论营养不良可导致慢性炎症进而在透析患者心血管并发症病情演变中起到重要作用。

Objective To study the relation between Hs - CRP and the IMT of carotid artery in MHD patients. Methods According to the level of ALB, 55 cases were divided into three groups at random, contrasted by control group with healthy people, the level of Hs - CRP and IMT of carotid artery were determined after treatment. Results With the decrease of the level of ALB, Hs - CRP and IMT both increased significantly, and there was a significant correlation between Hs - CRP and IMT. Conclusions Malnutrition may induce chronic inflammation and promoted the development of heart- blood diseases.