糖皮质激素治疗AECOPD 60例临床疗效分析

Clinical study of treatment effect of 60-case acute exacerbation of chronic obstruction pulmonary disease by using glucocorticostteroid

目的观察在综合治疗基础上,全身使用糖皮质激素对慢性阻塞性肺疾病急性加重期(AECOPD)患者的临床疗效。方法慢性阻塞性肺疾病急性加重期患者60例,随机分为对照组和治疗组,对照组给予氧疗、抗感染、止咳、祛痰等常规治疗,治疗组在上述治疗基础上加用全身糖皮质激素(静脉滴注甲基强的松龙和/口服强的松),组间进行疗效观察。结果全身糖皮质激素治疗组与对照组比较疗效差异具有显著性,疗效明显。结论在有力的抗感染、使用支气管扩张剂的基础上,短期、适量使用全身性糖皮质激素是有效、安全的。

To observe the clinical effects of glueoeortieostteroid on acute exacerbation of chronic obstructive pulmonary disease based on comprehensive treatment. Methods Sixty cases of acute exacerbation of chronic obstructive pulmonary disease were randomly divided into control group and treatment group. The control group was given regular treatment incluidng antibiotics, oxygen, cough relieving and expectoration. The treatment group was given, in addition to the treatment of the controls, the therapies using glucocorticostteroid. The two groups were compared. Results The significant difference was seen between the treatment group and the control group, with the effects favorable to the treatment group. Conclusion While using antibiotics, a short-term and proper use of glucocorticostteroid is safe and effective.