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肺癌患者外周血CD4^+CD25^+调节性T细胞检测及其临床意义 被引量：1

DETECTION OF CD4+,CD25+,T CELLS IN PERIPHERAL BLOOD OF PATIENTS WITH LUNG CANCER AND ITS CLINICAL SIGNIFICANCE
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摘要 目的了解肺癌患者外周血中CD4+CD25+调节性T淋巴细胞的比例和其临床意义,探讨CD4+CD25+调节性T细胞与临床分期的相关性。方法流式细胞分析仪检测外周血中CD4+CD25+调节性T细胞占CD4+T细胞的比例。结果肺癌患者外周血中CD4+CD25+调节性T细胞占CD4+T淋巴细胞的百分比为(15.7±1.6)%,明显高于健康对照者(7.1±1.5)(p<0.05),且外周血中CD4+CD25+调节性T细胞水平与患者病情分期呈显著正相关。结论肺癌患者外周血中具有免疫抑制活性的CD4+CD25+调节性T细胞比例较高,对肺癌患者具有免疫抑制功能。
作者 雷厉
机构地区 深圳市人民医院
出处 《现代医院》 2007年第9期72-73,共2页 Modern Hospitals
关键词 肺癌CD4^+ CD25^+调节性T细胞
分类号 R392.11 [医药卫生—免疫学]
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参考文献6

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二级参考文献43

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二级引证文献7

现代医院
2007年 第9期

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