摘要
肝豆状核变性又名Wilson病（WD），患者第13号染色体铜转运P型ATPase基因突变导致肝脏铜蓝蛋白合成障碍，体内过量的铜沉积于肝脏、脑、角膜和肾脏等部位，出现肝脏、神经系统、肾功能异常和角膜环等临床表现。如能早期行排铜治疗和低铜膳食，可获长期缓解，但对晚期患者，肝移植是目前最有效的治疗方法。
出处
《中华消化杂志》
CAS
CSCD
北大核心
2007年第8期551-551,共1页
Chinese Journal of Digestion
参考文献7
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同被引文献23
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1丛婷婷,贾胜男,唐丽敏,潘留兰.肝豆状核变性一例[J].中国综合临床,2017,33(2):165-166.
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5林连捷,郑长青.Wilson病的诊断和治疗[J].世界华人消化杂志,2003,11(10):1614-1617. 被引量：4
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6陈泽响,陆磊.帕金森病与糖尿病相关性研究进展[J].国际神经病学神经外科学杂志,2015,42(1):81-84. 被引量：4
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7郭庆军,朱志军,郑虹,李延钧,张建军,薛芳菁,侯建存,沈中阳.肝移植治疗肝性脊髓病三例[J].中华外科杂志,2007,45(23):1650-1650. 被引量：3
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8程东峰,彭承宏.肝移植治疗Wilson病的疗效[J].中华器官移植杂志,2005,26(5):319-320. 被引量：2
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9彭艳,蒋莉.难治性癫痫的危险因素[J].儿科药学杂志,2010,16(4):61-63. 被引量：1
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10崔园园,杨以良,王莎莎,华瑞.以精神障碍为首发症状的肝豆状核变性1例报告[J].临床肝胆病杂志,2016,32(11):2173-2174. 被引量：3
