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增龄对心房、肺静脉肌袖组织心肌细胞缝隙连接蛋白表达的影响 被引量:1

Affection of aging on connexin expression in atrial myocardium and myocardial sleeves of pulmonary veins
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摘要 广泛存在于动物体内的细胞通讯有两种方式,即通过释放信使物质执行远距离联络和通过相邻细胞之间的缝隙连接交换信息的接触联络。研究发现,心律失常的发生起源于细胞膜离子通道的紊乱和/或细胞间耦联(缝隙连接-Cx)的改变,甚至在某些情况下,缝隙连接耦联的改变更为重要。越来越多的研究资料显示,
出处 《中华心律失常学杂志》 2007年第4期305-306,共2页 Chinese Journal of Cardiac Arrhythmias
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同被引文献12

  • 1王健,刘兴鹏,刘小青,龙德勇,董建增,马长生.持续快速心房起搏对犬肺静脉及心房组织连接蛋白43和Ⅲ型胶原的影响[J].中华心血管病杂志,2005,33(3):269-272. 被引量:6
  • 2马骁,张薇,钟明,亓同刚,苗雅,孙慧,张运.心房颤动致犬肺静脉肌袖缝隙连接蛋白40表达降低[J].基础医学与临床,2006,26(4):392-395. 被引量:4
  • 3Jeffrey E, Saffitz H, Lee Kanter H, et al. Tissue specific determinants of anisotropic conduction velocity in canine atrial and ventricular myocardium [ J ]. Circ Res, 1994,74 : 1065
  • 4Yeh HI, Lai YJ, Lee YN , et al. Differential expression of connexin43 gap junctions in cardiomyocytes isolated from canine thoracic veins[J]. The Journal of Histochemistry&Cytochemistry, 2003,51 (2) :259
  • 5Verhule S, Wilson EE Arora R, et al. Tissue structure and connexin expression of canine pulmonary vein [J]. Cardiovase Res, 2002, 55 (4) : 727
  • 6Yeh HI, Lai YJ, Lee SH, et al. Remodeling of myocardial sleeve and gap junctions in caninc superior vena cava after rapid pacing [J]. Basic Res Cardiol, 2006, 101 (4) : 269
  • 7Shiroshita-Takeshita A, Sakabe M, Haugan K, et al. Mode-dependent effects of the gap junction conduction-enhancing antiarrhythmic peptide rotigaptide ( ZP123 ) on experimental atrial fibrillation in dogs[J]. Circulation, 2007, 115:310
  • 8Hamabe A, Okuyama Y, Miyauchi Y, et al. Correlation between anatomy and electrical activation in canine pulmonary veins [ J ]. Circulation,2003,107 ( 11 ) : 1550
  • 9Roux N, Havet E, Mertl P. The myocardial sleeves of the pulmonary veins: potential implications for atrial fibrillation [ J ]. Surg Radiol Anat, 2004,26(4) : 285
  • 10Tan AY, Li HM, Wachsmann-Hogiu S, et al. Autonomic innervation and segmental muscular disconnections at the human pulmonary vein-atrial junction[ J]. J Am Coll Cardiol,2006,48:132

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