血液透析患者营养不良、炎症和心血管疾病关系探讨

Discussion on the Relationship among Malnutrition,Inflammation and Cardiovascular diseases in Hemodialysis Patients

目的通过对维持性血液透析(MHD)患者进行营养不良、炎症和心血管疾病观察,探讨其发生率及相互关系。方法对142例血透患者进行一般情况、营养状况、慢性炎症和心血管疾病并发症等情况进行调查。其中以主观综合性营养评估(SGA)作为营养状况的标准,血CRP为慢性炎症的指标,影像学检查判断有无心血管疾病。结果142例血透患者中营养不良、炎症和心血管疾病发生率分别为:49.3%,24.0%,54.84%;营养不良、炎症、心血管疾病综合征19.0%;心血管疾病与炎症、营养不良呈正相关。结论营养不良、炎症、心血管疾病在维持性血液透析患者中是普遍存在的,三者间相互作用,并且加重心血管疾病的发生发展。

Objective To discuss the incidence of malnutrition, inflammation and cardiovascular diseases in hemodialysis patients and the correlation. Methods The general condition, the nutritional state, chronic inflammation and complications of cardiovascular diseases in 142 hemodlalysis patients were investigated, using SGA in assessing the nutrional state, CRP in assessing the chronic inflammation and imaging examination in assessing cardiovascular diseases. Restdts The incidence of malnutrition, inflammation and cardiovascular diseases in 142 patients was 49.3% ,24.0% and 54.84% respectively,and the incidence of Malnutrition- inflammation- Atherosclerosis （MIA） syndrome was 19.0%, ;cardiovascular diseases was positively related to malnutrition and inflammation, Conclusion Malnutrition, inflammation and cardiovascular diseases are common in hemodialysis patients;the 3 affect each other, and aggravate the incidence and development of cardiovascular diseases.