临床常见疾病中医证候要素分布特点的文献研究

Literature search of TCM syndrome elements of common diseases

目的:通过对临床5种常见疾病(抑郁症、慢性乙型肝炎、慢性肾功能衰竭、慢性阻塞性肺疾病、更年期综合征)的文献资料进行横向和纵向分析,总结出以文献为依据的常见疾病的证候要素分布规律。方法:遵循循证医学原则,采用EpiData3.0建立数据库对符合选择标准的文献进行二次录入,运用SPSS 12.0软件统计五种疾病证候要素出现的频次、频率。结果:①肝、心、脾、肺、肾是临床常见的病位证候要素。②阴虚、阳虚、热、气滞、气虚、血瘀、湿、痰是临床常见的病性证候要素。③五种疾病出现的证候类型个数在62-148之间,主要证候类型出现频率之和覆盖的疾病信息基本不足50%;而证候要素出现的个数在19-47之间,不论是常见病位要素还是病性要素出现频率之和覆盖的疾病信息基本在80%以上。结论:从证候要素入手进行中医证候的研究可以达到执简驭繁的作用,很有必要继续深入开展证候要素的研究。

Objective： To summarize the distributing rule of TCM syndrome elements of common diseases by analyzing the literature of Depression,Chronic Hepatitis B,Chronic Renal Failure,Chronic Obstructive Pulmonary Disease,Menopausal Syndrome.Methods： We selected eligible literatures,then established database with EpiData 3.0 software and computed the frequency of TCM syndrome elements with SPSS 12.0 software.Results： ①Liver,heart,spleen,lung and kidney are common TCM syndrome elements of location of disease.②Yin deficiency,yang deficiency,heat,qi stasis,qi deficiency,blood stasis,damp and phlegm are common TCM syndrome elements of nature of disease.③There are TCM syndrome types between 62 and 148,but the sum of frequency of leading syndrome types which includes disease information is mostly no more than 50%.There are TCM syndrome elements between 19 and 47,but the sum of frequency of leading syndrome elements which includes disease information is mostly above 80%.Conclusion： It is convenient to study TCM syndrome from the aspect of TCM syndrome elements,so we should thoroughly keep on studying TCM syndrome elements.