高血压患者血尿酸与脑梗死的相关性

Relationship between uric acid and cerebral infarction of patients with hypertension

目的探讨血尿酸水平对高血压患者发生脑梗死的预测价值。方法将住院确诊的肾功能正常的112例高血压病人根椐头颅CT或MRI检查结果分为脑梗死组33例,平均年龄(59.21±11.37)岁和无脑梗死组79例,平均年龄(44.92±9.82)岁。比较两组之间血尿酸浓度。结果与无脑梗死的高血压病人比较,脑梗死组年龄明显增高、高血压病程长(10.57±10.35)年vs(6.68±7.46)年,P<0.05)。脑梗死组与无脑梗死组收缩压(SBP)、舒张压(DBP)及血尿酸无明显差别(300.79±21.32)mmol/Lvs(358.78±36.54)mmol/L,P>0.05)。结论高血压患者发生脑梗死与年龄和病程有关;在肾功能正常的条件下,高血压患者发生脑梗死可能与血尿酸无相关性。

[Objective] To evaluate the relationship between uric acid and cerebral infarction of patients with hypertension. [Methods] Serum uric acid and other clinical data of 112 hypertension patients were collected. [Resuits] Age of patients and years of hypertension were positive correlated with cerebral infarction. Serum uric acid was negative correlated with cerebral infarction. [Conclusions] Cerebral infarction of patients with hypertension has relationship with Age and years of hypertension. It has no relationship with uric acid.