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他汀与血管紧张素Ⅱ受体阻断剂对血管内皮祖细胞影响的研究进展

Statins and Angiotensin Ⅱ Receptor Blocker Effects on Vascular Endothelial Progenitor Cells
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摘要 他汀、血管紧张素Ⅱ受体拮抗剂具有独立于降脂、控制血压以外的血管保护作用[1]。近几年的研究表明他汀与血管内皮祖细胞正性相关,同时提示了血管内皮祖细胞在增强血管再生和损伤血管的再内皮化过程中扮演着重要的角色;血管紧张素Ⅱ受体阻断剂对血管内皮祖细胞的影响有待进一步研究确定。 Statins and angiotensin Ⅱ receptor blocker （ ARB ） possess an additional cardiovascular protective activity independent of reduction of both cholesterol and blood pressure. Recent research has show that statins positively correlate with endothelial progenitor cells （ EPCs） , and it suggested that EPCs may play an important role in enhancing vascular regeneration and reendothelialization of vascular injuries. However, the beneficial effects on EPCs after ARB are yet to be clearly established.
作者 成小凤 陈明
机构地区 重庆医科大学附属第一医院
出处 《心血管病学进展》 CAS 2007年第5期805-808,共4页 Advances in Cardiovascular Diseases
关键词 他汀 血管紧张素Ⅱ受体阻断剂 内皮祖细胞 statins angiotensin Ⅱreceptor blocker endothelial progenitor cells
分类号 R96 [医药卫生—药理学]
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心血管病学进展
2007年 第5期

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