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结直肠癌组织中survivin和p53的表达及其关系 被引量:1

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摘要 选择结直肠癌组织和癌旁正常黏膜组织各40例份,采用免疫组化SP法检测其生存素(survivin)和p53。结果显示,survivin在结直肠癌组织中的阳性表达率为75.00%,癌旁组织均为阴性表达,两者相比,P<0.01 p53表达阳性的结直肠癌组织中survivin的阳性表达率明显高于p53表达阴性者,P<0.05。认为p53和survivin过度表达在结直肠癌的发生发展过程中起重要作用,且survivin的表达与p53的表达密切相关。
出处 《山东医药》 CAS 北大核心 2007年第24期69-70,共2页 Shandong Medical Journal
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参考文献5

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