监测感染指标在未足月胎膜早破处理中的意义

Clinical significance of monitoring infective indexes on management PPROM

目的探讨监测感染指标在未足月胎膜早破处理中的意义。方法对住院分娩的未足月胎膜早破（PPROM）96例和同期足月的胎膜早破（PROM）96例的临床资料进行分析，比较2组孕期、围产儿情况以及实验室感染指标监测情况。结果2组在入院孕周、分娩孕周、距分娩时间、新生儿体重、新生儿Apgar评分的比较差异有统计学意义（P〈0.05）；而孕妇年龄，新生儿死亡在二组间比较差异无统计学意义（P〉0.05）；白细胞计数、分类，C反应蛋白（CRP），胎盘胎膜病理检查、NST在二组间比较差异有统计学意义（P〈0.05）。结论在PPROM的积极期待治疗中，CRP、NST可作为监测感染的有效指标，能降低母儿并发症。一旦出现感染症状，就必须终止妊娠。

Objective To explore the significance of monitoring infective indexes on management PPROM. Method 96 cases of PPROM and 96 cases of PROM in Xin Hua hospital from Jan. 2002 to Dec. 2005 were retrospectively analyzed. The gestational periods, neonatal outcome and labor infective indexes were compared between two groups. Results There were no significant differences in the age of pregnancy women and the mortality of newborns between two groups. Significant differences were found on the newborn＇s weight and their Apgar＇s score, white blood cell, neutrophil, CRP, placental pathology between two groups. They could be used as indexes to monitor infection. Conclusion These laboratory item, such as CRP and NST, are of value in the prediction of chorioamnionitis and conservative treatment of PPROM.