小剂量瑞芬太尼复合异丙酚用于人工流产术

Propofol combined with aiverse dose remifentanli used for induced abortion

目的:观察异丙酚复合不同剂量瑞芬太尼静脉麻醉用于人工流产术的临床效果和安全性。方法:选择门诊ASA1-2级的早孕患者150例,分成三组,每组50例。A组,瑞芬太尼0.5mg/kg持续静注60s,随后静注异丙酚1.5mg/kg诱导,术中维持每次追加异丙酚0.5-1.0mg/kg;B组瑞芬太尼1.0mg/kg持续静注60s,随后静注异丙酚2.0mg/kg;C组单用异丙酚2.0mg/kg诱导,术中维持每次追加异丙酚0.5-1.0mg/kg。观察麻醉后收缩压(SBP)、舒张压(DBP)、心率(HR)、及血氧饱和度SpO2,记录手术持续时间、术闭下创离院的时间及异丙酚总用量,注射痛和术后宫缩痛的发生情况。结果:三组患者诱导后SBP、DBP、有所下降和HR减慢,注射痛和术后宫缩痛的发生率明显低于C组,异丙酚总量明显少于C组。结论:小剂量瑞芬太尼复合异丙酚静脉麻醉用于人工流产术具有麻醉效果好,镇痛作用强,呼吸抑制发生率低,能显著减少异丙酚用量等优点。

Objective：Observing efficiency and safety of propofol combined with diverse dose remifentanli is used for induced abortion.Methods： 150 early pregnancy patients were divided into 3 groups.A group is continuous injected remifantanli 0.5mg/Kg for 60 seconds and then injected propofol 1.5mg/Kg for induction, with 0.5 - 1.0mg/Kg propofol in maintaining every fime;B group is continuous injected remifantanli 1.0mg/Kg for 60 seconds and then injected propofol 2.0mg/Kg;C group is induced by propofiol 2.0mg/Kg, with 0.5- 1.0mg/Kg propofol in maintaining every time . Observing SBP, DBP, HR, SpO2 after anesthesia, noting operation time , leaving hospital time and total dose of propofol, the inject pain, the contraction pain. Results： Three group patients＇ SBP, D BP reduced, HR slow down after induction, the rate of inject pain,the contraction pain is less than C gronp. Conclusions： Minimum dose remifantanli combined with propofol is used for induced abordonhave some advantages of high analgesic effect,lower respiratory inhibition rate and reduced propofol dose.