短暂性脑缺血发作进展至脑梗死的相关因素分析

Analysis of the Predictors for Cerebral Infarction from Transient Ischemic Attack

目的:探讨短暂性脑缺血发作(TIA)发展至脑梗死的危险因素及临床干预的影响。方法:对220例TIA患者的临床资料进行分析。结果:发作频率在3次/d以上、发作持续时间超过30 min、神经功能缺损评分严重的病例、或伴有高血压、糖尿病或高血脂症是TIA短期内进展至脑梗死的危险因素。积极进行抗血小板聚集、抗凝或降纤治疗的患者发展至脑梗死的比例明显减少。结论:TIA反复发作、发作持续时间较长以及存在脑血管病危险因素的患者容易发生脑梗死。对TIA患者积极抗血栓治疗能明显降低脑梗死的危险性。

Objective： To study the risk factors for cerebral infarction resulting form transient ischemic attack（TIA）. Methods： The clinical data of 220 hospitalized patients with TIA were evaluated. Results： More than 3 attacks, attacks lasted longer than 30 minutes, serious nerve function damage, and hypertension, diabetes or hyperlipoidemia were identified as independent risk factors of cerebral infarction. Anti-platelet, anticoagulation, defibrination therapy was proven to be the factors which could lower the risk of cerebral infarction after TIA. Conclusion： Multiple attacks, prolonged ischemic duration, and more cerebral vascular disease risk factors indicate increased risk of stroke after TIA. Antithrombotic therapy is of great significance in preventing cerebral infarction after TIA.