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缺氧缺血性脑病患儿与正常新生儿血浆SOD、NSE含量比较

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摘要 目的探讨缺氧缺血性脑病患儿与正常新生儿之间超氧化物歧转化酶(SOD)及神经元特异性稀醇化酶(NSE)的含量变化。方法选HIE患儿96例,其中轻度49例,中度34例,重度13例。另选同期出生的正常新生儿76例,均于生后第3天测血清中SOD及NSE的含量。比较其结果。结果缺氧缺血性脑病患儿较正常新生儿血液中SOD水平明显下降、NSE水平明显增高(P均<0.01),且重度HIE患儿比中度HIE患儿变化明显(P<0.05)。中度比轻度变化明显,且有统计学意义P<0.01。结论可以通过测定血中NSE及SOD的值来了解脑缺氧损伤的严重程度。
作者 屈平 杨书芹
出处 《河北医药》 CAS 2007年第8期819-819,共1页 Hebei Medical Journal
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