糖尿病患者外周血管病变的特征

The characteristics of peripheral artery disease in type 2 diabetes mellitus

目的观察糖尿病患者的外周动脉的病变特征。方法采用彩色多普勒超声技术对糖尿病(DM)患者及非糖尿病(N-DM)患者的外周动脉粥样硬化斑块、狭窄以及闭塞性病变特征进行观察。结果与N-DM组比较,DM组外周动脉的内-中膜厚度(IMT)、狭窄血管大小、血管闭塞率、闭塞血管大小及闭塞血管回声差异无统计学意义,但斑块总面积显著增加(P<0.05),斑块回声积分显著减小(P<0.01),血管狭窄率显著增加(P<0.01)。结论糖尿病可使患者的外周动脉粥样硬化病变更严重,使中型动脉的狭窄几率更高,但闭塞性病变与非糖尿病患者无差异。

Objective To examine the characteristics of peripheral artery disease in patients with type 2 diabetes mellitus（T2DM）.Methods By using colour Dopple ultrasonography,we observed the characteristics of atherosclerotic plaque,narrowness and occlusion of peripheral arteries.Results Although there was no significant difference in intima-media thickness（IMT）,location of narrow,rate of occlusion,occlusive location and echo of occlusive arteries between groups of T2DM and N-DM,there was significant increase in total area of plaque（P〈0.05） and significant decrease in echo of plaque（P〈0.01） and significant increase in rate of narrow induced by atherosclerotic plaque in patients with T2DM.Conclusions There were more serious changes of atherosclerosis in peripheral artery and higher rate of narrow in medium-sized artery,however,there was similar change of occlusion.