微量白蛋白尿与2型糖尿病患者臂踝脉搏波传播速度和颈动脉内中膜厚度的关系

Relationship of microalbuminuria with brachial ankle pulse wave velocity and carotid intima-media thickness in type 2 diabetic patients

2型糖尿病微量白蛋白尿者(MAU)42例,正常白蛋白尿者118例。MAU组年龄较大,血压、臂踝脉搏波传播速度(baPWV)和颈动脉内中膜厚度(IMT)均较高(P均<0.05),MAU正相关于baPWV和IMT(r分别为0.58、0.56),校正相关参数后多因素分析显示,仅MAU与baPWV和IMT独立相关。MAU与2型糖尿病的动脉粥样硬化相关。

In type 2 diabetic patients with microalbuminuria（n=42） and normoalbuminuria（n=118）,brachial ankle puse wave velocity（baPWV） and intima-media thickness（IMT） were measured.Results showed that patients with microalbuminuria were significantly older,had higher levels of blood pressure,baPWV and IMT（P〈0.05,respectively）.Microalbuminuria was correlated positively with baPWV and IMT（r=0.58,0.56;P〈0.05,respectively）.After parameter adjustments,multivariate analysis showed that only microalbuminuria was independently associated with baPWV and IMT（all P〈0.005,respectively）.In Microalbuminuria correlates with artherosclerosis in type 2 diabetes.