儿童幽门螺杆菌感染与缺铁性贫血的关系

Clinical Study of Correlation between Helicobacter Pylori Infection and Iron Deficiency Anemia in Children

目的探讨儿童幽门螺杆菌(Hp)感染与缺铁性贫血(IDA)之间的关系。方法对90例有消化道症状的患儿进行胃镜检查和Hp检测,根据检查结果分为Hp阳性观察组和Hp阴性对照组。病例均检测血常规、血清铁(SI)、血清铁蛋白(SF)、总铁结合力(TIBC)等IDA指标。结果观察组44例中IDA23例,IDA发病率为52.27%;对照组46例中IDA8例,IDA发病率为17.39%;二者比较差异有统计学意义(χ2=12.12P<0.05)。结论儿童Hp感染与缺铁性贫血有关,Hp感染可能为IDA的发病因素之一。

Objective To study the relationship between helicobocter pylori（Hp）infection and iron deficiency anemia（IDA）in children.Methods Children who had upper digestive symptom were had gastroscopy examination and Hp test.According to the examination results,all the patients were divi-ded into 2 groups,the observation group and the control group.All patients were detected blood routine,serum iron（SI）,serum ftrritin（SF）and total iron-binding capacity（TIBC）.Results The IDA morbidity was 52.27%（23/44 cases）in obsorvation group and 17.39%（8/46 cases）in control group,there was obvious difference between two groups（χ^2=12.12 P〈0.05）.Conclusion There is obvious relationship between Hp infection and IDA in children.