妇血宁合剂治疗血瘀型崩漏临床观察

Clinical Study of Fuxueningheji in Treating Metrorrhagia of Blood Stasis Syndrome

目的观察妇血宁合剂对血瘀型崩漏的临床疗效,并探讨其止血机理。方法将60例血瘀型崩漏患者单盲法随机分为治疗组和对照组。治疗组用妇血宁合剂,对照组用宫血宁胶囊治疗,1个月为1个疗程,并比较其疗效。结果总有效率治疗组为93.33%,愈显率为80%;对照组总有效率为66.67%,愈显率为40%。2组总有效率比较,P>0.05;愈显率比较,P<0.05。妇血宁合剂能缩短出、凝血时间,改善血液流变性;降低前列环素,提高血栓素B2,作用优于对照组,差异具有显著性(P<0.01或P<0.05)。结论妇血宁合剂对血瘀型崩漏有良好的止血作用。

Objective To observe the curative effects and explore the homeostasis mechanism of Fuxueningheji in treating metrorrhagia with blood stasis. Methods 60 patients were divided randomly into test group （30 cases, treated with Fuxueningheji） and control group （30 cases, treated with Gongxuening pulse）, one course was 1 month. ~ The total effective rate of treatment group was 93.33%, and markedly effective rate was 66.67%, while the control group was 66.67% and 40% respectively. There was no significant difference in total effective rate, but was significant difference in markedly effective rate. Fuxueningheji could improve clinical symptoms of patients obviously and reduced the bleeding and coagulation time, improve the hemorheology, decrease PGI2, increase TXB2. The effects was superior to that of the control group （P〈0.01 or P〈0.05）. Conclusion Fuxueningheji is effective in treating metrorrhagia with blood stasis syndrome.