摘要
目的探讨核素心肌显像对骨髓干细胞(MSCS)移植治疗急性心肌梗死(AM I)的效果评价。方法将48例AM I患者随机分为观察组及对照组,两组均行急诊经皮冠状动脉介入加药物治疗,观察组加行MSCS移植。治疗前后用核素心肌显像技术观察两组心功能及心肌梗死(M I)面积改善情况。结果与对照组比较,观察组心功能明显改善,M I面积明显缩小(P<0.05)。结论MSCS移植治疗AM I的疗效显著优于常规疗法;核素心肌显像对MSCS移植前后AM I患者的疗效及预后判断有重要价值。
[ Objiective ]To investigate nuclide-myocardial imaging evaluating effect of bone marrow stem cell transplant treating acute myocardial infraction （AMI）. [ Methods ] 48 cases of AMI patients were randomly divided into survey group and control group, they .all received emergency treatmengt of percutaneous coronary artery intervention and medicine. In survey group ,bone marrow stem cell transplant（MSCS） was added. Heart function and myocardial infarction （MI） areas improvement status in two groups were observed by nuclide myocardial imaging in prctherapy and post- treatment. [ Results ] In comparison to control group, heart function improved obviously and MI area diminished （P 〈 0.05 ）. [Conclusion] Therapeutic effect of MSCS transplant treating AMI outweighs conventional therapy; nuclide myocardial imaging plays an important role in valuing therapeutic effect and prognosis of AMI patients before or after MSCS transplant.
出处
《山东医药》
CAS
北大核心
2007年第25期19-20,共2页
Shandong Medical Journal
基金
国家高技术研究发展计划(863计划)(2005AA205232)
关键词
心肌梗死
急性
骨髓祖代细胞
核素心肌显像
myocardial infarction, acute
myeloid progenitor cell
nuclide myocardial imaging
