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亚低温对正常人单核细胞体外合成细胞因子的影响 被引量:3

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摘要 在内毒素(LPS)诱导下,用ELISA法检测10例正常志愿者正常温度(37℃)及亚低温(33℃)下单核细胞体外合成细胞因子TNF-α、IL-6、IL-8、IL-10、IL-12水平,以及IL-12/IL-10、IL-6/IL-10与TNF-α/IL-10比值。结果显示,与37℃条件下比较,单核细胞在33℃条件下48 h分泌的TNF-α、IL-6、IL-12明显升高,且IL-12/IL-10与TNF-α/IL-10比值明显升高(P<0.05)。提示亚低温可促进单核细胞分泌促炎细胞因子TNF-α、IL-12,使IL-12/IL-10与TNF-α/IL-10比值升高,导致炎性反应。
出处 《山东医药》 CAS 北大核心 2007年第25期44-45,共2页 Shandong Medical Journal
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同被引文献44

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