黛力新结合心理早操、音乐干预对鼻咽癌放疗患者临床疗效的影响

Clinical intervention of the combined application of deanxit, mental morning exercise and music on nasopharyngeal carcinoma patients under radiotherapy

目的探讨应用黛力新结合音乐疗法、心理早操综合治疗对鼻咽癌放疗期间病人生活质量以及心理健康、免疫功能的影响。方法将132例鼻咽癌放疗病人随机分为实验组67例和对照组65例,实验组接受与对照组相同常规放疗外还接受黛力新治疗同时结合音乐、心理早操至放疗结束,对照组单纯行常规放疗。观察2组临床疗效及检测2组放疗前及放疗后6个月和12个月的疗效随访资料进行对比分析。结果鼻咽癌放疗病人的生活质量状况以放疗前最好,放疗后12个月次之,放疗后6个月最差,经过黛力新结合心理早操和音乐等综合临床干预的鼻咽癌放疗病人放疗后其生活质量各功能指标均明显提高,其免疫功能也明显提高,放疗后6个月以心理情绪状况明显改善为主。放疗后2组比较,实验组的CD3,CD4,CD4/CD8及NK细胞活性高于对照组,实验组的HAMA和HAMD值分别为（5.06±2.67）分和（10.06±2.67）分,明显低于对照组的[（16.93±3.88）分和（26.23±3.68）分],同时实验组SF-36评分各亚项的评分躯体功能[（61.7±24.4）分]躯体角色[（19.1±32.6）分]肌体疼痛[（61.2±22.1）分]总健康[（54.2±21.4）分]生命力[（64.2±22.5）分]社会功能[（55.1±24.3）分]情感角色[（54.3±42.1）分]心理健康[（66.5±15.1）分]明显高于对照组的躯体功能、躯体角色、肌体疼痛、总健康、生命力、社会功能、情感角色、心理健康的得分。结论黛力新结合心理早操和音乐疗法这种临床干预方法简便实用,可以明显提高生活质量和机体免疫功能,改善心理状况。

Objective To explore the clinical effect of the combined application of deanxit, mental morning exercise and music on the life quality, mental health and immune function of nasopharyngeal carcinoma patients under radiotherapy. Methods 132 cases nasopharyngeal carcinoma patients under radiotherapy were randomly divided into experiment group（67 cases） and control group（65 cases）. Experiment group was applied with the combined application of deanxit, mental morning exercise and music besides routine radiotherapy. Control group was applied with radiotherapy only. Contrast analysis of therapeutic effect of both groups on 6 months and 12 months after check out were performed. Results The life quality of nasopharyngeal carcinoma patients goes worse during radiotherapy. The combined application of deanxit, mental morning exercise and music can improve the life quality of nasopharyngeal carcinoma patients and boost the immune function, especially the improvement of mental conditions. Conclusion The combined application of deanxit, mental morning exercise and music is convenient , can improve the life quality ,immune function and the mental condition, which help the recovery of patients.