单剂疗法和10天疗法治疗尿路感染疗效对比分析

Contrasting the curative effect of single-dose therapy with that of ten-day therapy in curing urethral infection

对比治疗尿路感染的疗法的疗效。方法 将女性尿路感染患者进行随机双盲分组,使用复方新诺明单剂治疗与10天治疗。同时测定两组各期阴道,肠道大肠杆菌感染情况。结果 开始治疗两周内,10天治疗治愈率明显高于单剂治疗组(P<0.05)。6周后后治愈率相近。在根绝阴道和肠道细菌方面,单剂治疗效果较差,导致治疗两周内同种菌株复发率增高。10天治疗副作用高于单剂治疗组(P<0.05)。结论 单剂及10天疗法各有优缺点。

To compare the effect of single-dose therapy with ten-day therapy in curing urethral infection. Methods 127 female urethral infection patients were divided into groups at random, accepted SMZ co. single-dose therapy and ten-day therapy separately. In (he mean time, vaginal and intestinal ooli infection at each phase of the two groups was determined. Results '1 he cure rate of the group receiving ten-day therapy was obviously higher than that of the group accepting single dase therapy( P <0.05) in the first twoweek treatment. Hut their cure rates became close after six-week treatment. The worse curative effect of single-dose therapy in eradicating vaginal bacteria and intestinal bacteria probably resulted in the increase of relapsing rate of the same liacterium in two-week treatment. Gmclusion Single-dose and ten-day therapy have their own advantages and defects respectively.