头颈部副神经节瘤的分子生物学
摘要
副神经节瘤中有10％～50％为遗传性疾病。琥珀酸脱氢酶B、C、D亚单位基因突变可造成线粒体复合体Ⅱ结构和构象的改变，导致其功能减低或完全失活，引起氧传感通路异常及凋亡调控障碍，在头颈部家族性及散发性副神经节瘤的发病中均发挥重要作用。
出处
《国际耳鼻咽喉头颈外科杂志》
2007年第5期298-300,共3页
International Journal of Otolaryngology-Head and Neck Surgery
参考文献18
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