期刊文献+

蝎毒及其提取物免疫调节及抗肿瘤免疫作用

Effect of scorpion venom and it' s extracts on immunity modulation and anti-tumor immunity
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摘要 蝎毒及其提取物对多种肿瘤具有抗肿瘤作用,近年来研究资料表明,蝎毒提取物对机体具有免疫调节作用,并能提高肿瘤机体的抗肿瘤免疫反应。 Scorpion venom and it' s abstracts have anti-tumor effect in many kinds of tumors, Recent studies show scorpion venom and it' s extracts have immunity modulation effect, and can improve anti-tumor immunity response.
出处 《国际肿瘤学杂志》 CAS 2007年第8期583-586,共4页 Journal of International Oncology
基金 国家自然基金资助项目(30371841)
关键词 肿瘤 免疫 淋巴细胞 树突细胞 Neoolasms Immunity Lvmohocytes Dendritic cells
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参考文献20

  • 1Matsuda H, Toguchida I, Ninonliya K, et al. Effect of sesquitepenes and amino acid-sesquiterpene conjugates from the roots fo saussurea lappa on inducible nitric oxide synthase and heat shock protein in lipopolysaccharide- activated macrophages. Bioorg Med Chem, 2003, 11 (5) :709-715.
  • 2Petricevich VL, Lebrun I. Immunomodulatory effects of the Tityus serrulatus venom on murine macrophage functions in vitro. Mediators Inflamm ,2005,2005 ( 1 ) :39-49.
  • 3Petricevich VL. Effect of Tityus serrulatus venom on cytokine production and the activity of murine macrophages. Mediators Inflamm, 2002, 11(1) :23-31.
  • 4Bagdany M, Batista CV, Valdez-Cruz NA, et al. Anuroctoxin, a new scorpion toxin of the α-KTx 6 subfamily, is highly selective for Kv1. 3 over IKCal ion channels of human T lymphocytes. Mol Pharmacol, 2005,67(4) :1034-1044.
  • 5张维东,张月英,王朝霞,王兆朋,贾青.蝎毒多肽提取物对肿瘤生长和细胞免疫功能的影响[J].山东大学学报(医学版),2007,45(3):286-289. 被引量:27
  • 6Gordon IO, Freedman RS. Defective antitumor function of monocytederived macrophages from epithelial ovarian cancer patients. Clin Cancer Res,2006,12(5 ) :1515-1524.
  • 7Clemenceau B, Congy-Jolivet N, Gallot G, et al. Autibody-dependent cellular cytotoxicity ( ADCC ) is mediated by genetically modified anti- genspecific human T lymphocytes. Blood, 2006,107 ( 12 ) :4669 -4677.
  • 8Liyanage UK, Moore TY, Joo HG, et al. Prevalenc of regulatory T cells is increased in peripheral blood and tumor microenvironment of patients with pancreas or breast adenocarcinoma. J Immunol, 2002, 169 (5) : 2756-2761.
  • 9Kim ES, Kim MS, Moon A. Transforming growth factor(TGF)-beta in conjunction with H-ras activation promotes malignant progression of MC F 10 A breast epithelial cells. Cytokine, 2005,29 ( 2 ) : 84 -91.
  • 10Loh JK, Hwang SL, Lieu AS, et al. The alteration of prostaglandin E2 levels in patients with brain tumors before and after tumor removal. J Neurooncol,2002,57 (2) : 147-150.

二级参考文献26

  • 1孔天翰,董伟华,田中岭.全蝎及蝎毒抗肿瘤研究进展[J].河南肿瘤学杂志,1994,7(3):244-247. 被引量:25
  • 2张维东,崔亚洲,贾青,宋守芹,王朝霞,董强.蝎毒多肽提取物对小鼠S_(180)肉瘤和H_(22)肝癌血管生成抑制作用的实验研究[J].山东中医药大学学报,2005,29(2):152-155. 被引量:24
  • 3张维东,崔亚洲,姚成芳,贾青,宋守琴,王朝霞,董强.蝎毒多肽提取物抗肿瘤血管生成作用的实验研究[J].中国药理学通报,2005,21(6):708-711. 被引量:56
  • 4王兆朋,张维东,张捷,贾青,宋守琴,王朝霞,黄山英,张月英.蝎毒多肽提取物对非激素依赖性前列腺癌细胞增殖抑制作用的实验研究[J].中国药理学通报,2006,22(8):938-942. 被引量:19
  • 5Crompton NE,Ozsabin M. A versatile and rapid assay to radiosensitivity of peripheral blood leukocyte based on DNA and surface marker assessment of cytotoxicity. Radiat Res,1997,147:55-60.
  • 6Strong PN,Clark GS,Armugan A,et al.Tamulustoxin:a novel potassium channel blocker from the venom of the Indian red scorpin Mesobuthus tamulus.Arch Biochem Biophys,2001,385(1):138-144.
  • 7Lepple-Wienhues A,Berweck S,Rohming M,et al.K^+ channels and the intracellular calcium signal in human melanoma cell proliferation. J Membr Biol,1996,15:149-157.
  • 8Devaux C,Moreau E,Goyffon M,et al.Construction and functional evaluation of a single-chain antibody fragment that neutralizes toxin AahI the venom of the scorpion Androctonus australis hector. Eur J Biochem,2001,268:694-702.
  • 9Nakamura N,Kusunoki Y,Akiyama M.Radiosensitivity of CD4 or CD8 positive human T lymphocytes by an in vitro colony formation assay. Radiat Res,1990,23:224-227.
  • 10Seki H,Iwai K,Kanegane H,et al.Differential protctive action of cytokines on radiation-induced apoptosis of peripheral lymphocyte subopulations. Cell Immunol,1995,163:30-36.

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