硒、维生素B_1对雏鸡串珠镰刀菌素中毒的影响

Effects of Selenium and Vitamin B 1 on the Moniliformin Toxicosis in Chicks

用含有串珠镰刀菌素７６．９８ｍｇ／ｋｇ的饲料饲喂１０日龄雏鸡，引起中毒和７０％的雏鸡死亡，全血ＧＳＨ－Ｐｘ，血浆ＧＯＴ、ＧＰＴ、ＡＫＰ，丙酮酸，钾，钠均发生变化。加入０．２ｍｇ／ｋｇ亚硒酸钠，死亡率降为４６．６７％，细胞膜损害较轻。加入２０ｍｇ／ｋｇ维生素Ｂ１，死亡率降为５０％，心肌线粒体数量增加。结果表明。

day old chicks fed diet containing 76.98 mg/kg moniliformin (MON) were intoxicated, 70% of which died. The activities of the whole blood GSH Px, the plasma GOT, GPT, AKP and the concentrations of the plasma acetyl formic acid, K +, Na + were changed. When 0.2 mg/kg sodium selenite was added to the diet, the mortality was decreased to 46.67% and the cytomembranes damage was eased. While 20 mg/kg Vitamin B 1 was added to the diet, the death rate reduced to 50% and the numbers of mitochondrias was raised in myocardium. The results showed that the supplement of selenium and Vitamin B 1 can lighten the toxic effects of moniliformin on the chicks.