聚维酮碘诱导与杀灭铜绿假单胞菌L型的实验观察

Experimental observation on povidone iodine to induce and to kill L-type aeruginous bacillus

[目的]了解聚维酮碘诱导与杀灭铜绿假单胞菌L型的效果。[方法]用悬液法进行L型菌诱导与杀灭试验。[结果]以含500mg/L有效碘的聚维酮碘作用1min～5min、1000mg/L有效碘的聚维酮碘作用1min可诱导铜绿假单胞菌形成L型;对原菌株与L型的最小抑菌浓度分别为62.500mg/L与125.000mg/L。[结论]消毒应用的聚维酮碘剂量应高于用铜绿假单胞菌原菌株测得的杀灭合格的剂量。

Objective： To know the effect of povidone iodine to induce and to kill L- type aeruginosus bacillus. Methods： Suspension method was applied to induce and to kill L - type aeruginosus bacillus. Results： Povidone iodine can induce aeruginosus bacillus to become L- type in 500 mg/L for 1 to 5 minute and 1000 mg/L for I minute. The minimal antiblastie con- centration of povidone iodine to primary and L - type bacillus are 62. 500 mg/L and 125. 000 mg/L respectively. Conclusion： The dosage of povidone iodine for disinfection should be higher than that of killing aeruginosus bacillus normal strains.