摘要
为了验证咳宁冲剂的抗呼吸道感染作用,实验观察了中药咳宁冲剂抗菌作用以及其对免疫功能的影响。体外杯碟法实验中咳宁0.1～0.3g/ml能抑制五种常见呼吸道病原菌生长,试管法中咳宁的最小杀菌浓度为0.05g/ml;咳宁3g/kg等显著减低腹腔注射金葡菌所致小鼠的死亡率。咳宁3g/kg和1.5g/kg均能显著抑制小鼠血清溶血素生成和增强DNFB所致的迟发性超敏反应,对腹腔巨噬细胞吞噬功能无显著影响。由此证实咳宁冲剂为治疗呼吸道感染性疾病的有效药物。
In order to test the anti-inflammation effect of kening infusion, antibacterial effect of Kening infusion (A Chinese drug) and it's influence on immunologic function of mice. Observing the anti-inflammation and immunity experiment. The results showed that, kening infusion (0. 1-0. 3g/ ml) had bacteriostasis on five pathogenic bacterum in test cupping method and it's minimal bac-teri-cidal concentration (MBC) was 0. 05g/ml in test tube one. Kening (3g/Kg) could obviously lower mortality of mouse with intraperitonealab-domnal injection of Staphy-lococcus. kening (3g/ Kg &- 1. 5g/Kg) could inhibite the production of serum hemolysin and enforce delayed hypersensi-tivity induced by DNFB in mouse without significant effect on macrophage phagocytic function in abdominal cavity.
出处
《中国中医药科技》
CAS
1997年第2期80-82,共3页
Chinese Journal of Traditional Medical Science and Technology
