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白细胞介素-18及其抗肿瘤作用 被引量:3

IL-18 and its antineoplastic activity
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摘要 白细胞介素-18(IL-18)是新近发现的一种多效能细胞因子,在刺激T细胞增殖,增强Th、细胞毒性T细胞和自然杀伤细胞等活性,抗肿瘤、免疫调节等方面有着积极的作用,有潜在广阔的应用前景。进一步研究IL-18抑制肿瘤的机制及其生物学作用具有重要的意义。 IL-18 is one of the latest discoveries of pleiotropic cytokine, which can promote T cells proliferation and enhance the activity of Th cell, CTL cell and NK cell. It plays an active role in antitumor and immunoregulation. There might be a variety of potentialities of its application. It is necessary to further investigate the mechanisms of antitumor and biological effects of IL-18.
出处 《国际肿瘤学杂志》 CAS 2007年第9期644-647,共4页 Journal of International Oncology
基金 福建省自然科学基金计划资助项目(2006J0342)
关键词 白细胞介素-18 肿瘤 细胞因子类 Interleukin-18 Neoplasms Cytokines
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