促红细胞生成素对外伤性脑损伤的保护作用
被引量：1
摘要
促红细胞生成素(Erythropoietin,EPO)除了促进红细胞成长以外,还具有抗炎、抗细胞凋亡、神经营养和神经保护作用;中枢神经系统(CNS)中的星形胶质细胞可以通过旁分泌方式分泌EPO,然后通过EPO-R发挥作用;EPO在外伤性颅脑损伤中具有抗凋亡、减轻脑水肿、促进神经细胞再生、减少兴奋性氨基酸神经毒性及抗氧化的作用;新型外源性EPO能透过血脑屏障,其临床应用前景看好。
出处
《国际神经病学神经外科学杂志》
2007年第4期381-384,共4页
Journal of International Neurology and Neurosurgery
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