猫人参化学成分的研究

Studies on chemical constituents from root of Actinidia macrosperma

目的:研究猫人参(大籽猕猴桃)的化学成分。方法:利用正相和反相硅胶及Sephadex LH-20等色谱技术反复分离纯化,用波谱数据及理化性质确定其结构。结果:从猫人参乙醇提取物的醋酸乙酯萃取部分得到8个化合物,其结构分别鉴定为:2α,3α,24-三羟基-12烯-齐墩果烷(1),isotachioside(2),积雪草酸(3),儿茶素(4),表儿茶素(5),熊果酸(6),胡萝卜苷(7),β-谷甾醇(8)。结论:以上化合物均为从该植物中首次获得,其中化合物1,2为首次从猕猴桃属植物中分离得到。

Objective： To study the chemical constituents of root of Actinidia macrosperma. Method： Chromatographic methods were used to isolate compounds from A. macrosperma and spectroscopic methods were used to identify the structures of the isolated compounds. Result： Eight compounds were obtained and identified as 12-oleanene-2α, 3α, 24-triol （1）, isotachioside （2）, asiatic acid （3）, catechin （4）, epicatechin （5）, ursolic acid （6）, β-daucosterol （7）, β-sitosterol （8）. Conclusion： All these com- pounds were isolated from this plant for the first time, compound 1, 2 were obtained from this genus for the first time.