急性ST段抬高心肌梗死小血管病变急诊经皮冠状动脉介入治疗应用雷帕霉素药物洗脱支架的疗效分析

Application of sirolimus-eluting stent to small coronary artery lesions with acute ST-segment elevation myocardial infarction treated by emergency percutaneous coronary intervention

目的探讨雷帕霉素药物洗脱支架在急性ST段抬高心肌梗死(STEMI)小血管病变患者急诊经皮冠状动脉介入治疗(PCI)中应用的安全性和有效性。方法对121例STEMI小血管病变患者128处罪犯病变行PCI治疗,共置入了136枚雷帕霉素药物洗脱支架。结果121例PCI均成功,未发生与PCI有关的并发症。1例术后第2天死于心脏破裂,未发生主要不良心血管事件。进行12个月临床随访,有2例术后5个月再次行冠状动脉血运重建术,无其他主要不良心血管事件发生。结论雷帕霉素药物洗脱支架在STEMI小血管病变患者急诊PCI中应用有较高的安全性和有效性。

Objective To investigate the feasibility, safety and efficacy of sirolimus - eluting stent implantation in small conronary artery lesions with acute ST - segment elevation myocardial infarction （STEMI） treated by emergency percutaneous coronary intervention （ PCI） . Methods 128 target lesions of 121 small conronary artery lesions patients with STEMI were treated by emergency PCI. 136 sirolimus - eluting stents were successfully implanted. Results 121 patients were sucessfully treated by emergency PCI and there were no complications during the procedure. The successful rates were 100%. One patient died of cardiac rapture two days after the operation. 120 discharged patients were followed up 12 months. During follow up, two patients accepted reintervention 5 months after the operation. Conclusion Sirolimus -eluting stents implantation in small conronary artery lesions with STEMI treated by emergency PCI was safe and effective .