2964例女性原发性骨质疏松检出率分析

Clinical analysis of the primary osteoporosis prevalence in 2964 women

目的探讨原发性骨质疏松的易患因素,为预防骨质疏松的发生提供依据。方法采用Hologic QDR 2000型双能X线骨密度仪（DEXA）,检测2964例28～90岁门诊女性患者腰椎正位（L_（1-4））、髋部（股骨颈、大转子、转子间、Ward三角）的骨密度,以t〈-2.5s为骨质疏松诊断标准。结果2964例中,骨质疏松1968例（66.4%）。随增龄骨质疏松的检出率增加,28～39、40～49、50～59、60～69、70～79和80～90岁组骨质疏松检出率分别为10.7%、20.8%、45.1%、81.3%、95.1%和97.4%;骨质疏松的检出率随着身高增高而减低,身高140～149、150～159、160～169、170～180 cm骨质疏松的检出率分别为93.4%、73.1%、56.6%、24.3%;体质量下降、绝经时限的延长,骨质疏松的检出率增高。不同症状、不同职业骨质疏松的检出率亦有差别。结论骨质疏松的检出率与年龄、身高、体质量、绝经时限、症状、职业有关。

Objective To investigate susceptible factor for primary osteoporosis and look for the scientific basis for prevention of osteoporosis.Methods Bone mineral density（BMD）of lumbar 1-4 and proximal femur（Neck,Troch,Inter,Ward＇s）in 2964 women aged 28-90 years were measured with Hologic QDR 2000 dual energy X-ray absorptiometer.Osteoporosis was diagnosed on the basis of BMD t value〈-2.5 s in this study.Results Nineteen hundred and sixty eight of the 2964 measured cases were osteoporosis and the prevalence rate of osteoporosis was 66.4%.The rate of osteoporosis was increasing with aging（10.7% in 28-39 years old group,20.8% in 40-49 years old group,45.1% in 50-59 years old group,81.3%in 60-69 years old group,95.1% in 80-79 years old group and 97.4% in 80-90 years old group,respectively],with the body height decreasing[24.3% in 170-180 cm group,56.6% in 160-169 cm group,73.1% in 150-159 cm group,93.4% in 140-149 cm group,respectively],and with the body weight decreasing and with the menopause duration increasing.There were significant differences in the prevalence rate of osteoporosis with changes of age,height,weight,menopause duration,symptoms and occupation.Conclusions Age,height, weight,menopause duration,symptoms and occupation are related factors for osteoporosis.