高强度聚焦超声在医学超声领域中的发展与应用

The development and application of high intensity focused ultrasound in biomedical ultrasonics

高强度聚焦超声(high intensity focused ultrasound,简称HIFU)作为一种非侵入性、无毒副作用、具有巨大潜力的治疗肿瘤的手段,近年来已经越来越受到国内外学者的广泛关注。HIFU技术能将超声能量聚焦到人体组织的肿瘤内,产生高温,使肿瘤组织温度迅速上升至65℃以上,而发生不可逆转的凝固性坏死,从而达到消融肿瘤组织的目的。目前中国的HIFU肿瘤治疗技术和临床居国际领先。文章对HIFU在医学超声领域中的发展历史、现状和前景进行了探讨。

High intensity focused ultrasound as a nondestructive method without side-effects for tumor therapy has attracted wide interest. The theory is based on the focusing of low-energy ultrasound onto the desired region in the body in order to raise the tumor temperature to above 65℃, thereby inducing ablation. China is among the foremost in thisfield, including clinical application. The history and development of high intensity focused ultrasonics is reviewed.