颈动脉内中膜厚度及斑块与冠心病的关系

Association of Carotid Artery Intima-Media Thickness and Plaque Score with Coronary Heart Disease

目的通过对颈动脉内中膜厚度(intima-media thickness,IMT)及斑块检出,探讨颈动脉硬化与冠心病(CHD)的相关性。方法应用彩色多普勒超声成像仪对149例疑似冠心病者测定IMT及对斑块分级,并通过冠状动脉造影(CAG)检查分为冠心病组99例和非冠心病组50例,比较两组间颈动脉IMT、斑块指数及颈动脉斑块检出率。结果冠心病组颈动脉IMT(t=2.578)、斑块指数(t=3.182)显著高于非冠心病组(P<0.01);冠心病组颈动脉粥样硬化斑块检出率较非冠心病组明显增高。结论颈动脉粥样硬化斑块与冠心病密切相关,是及早预测冠心病的一个较好指标。

Objective To investigate the relationship between cervical atherosclerosis and coronary heart disease（CHD） through detecting intima-media thickness（IMT） and plaque in carotid artery.Methods The carotid IMT and plaque score were measured in 149 patients with suspected CHD by color Doppler flow imagining and all the patients were divided into CHD group（99 cases） and non-CHD group（50 cases） by coronary angiography（CAG）.Carotid IMT,the plaque index and the detection rate of carotid plaque were compared between CHD group and non-CHD group.Results The carotid IMT（t=2.578）and plaque index（t=3.182） of CHD group were significantly higher than those of non-CHD group（P〈0.01）.The detection rate of carotid plaque of CHD group was very higher than those of non-CHD group.Conclusions There is close correlation between carotid atheromatous plaque and CHD,so the carotid atheromatous plaque is an effective parameter for early prediction of CHD.