设计类固醇兴奋剂的特征分析及发展预测

Feature Analysis and Future Perspective of Designer Steroid

目的:针对设计类固醇兴奋剂,分析并探讨其设计特点和发展趋势。方法:文献资料法和理论分析法。结论:设计类固醇兴奋剂是一些没有纳入世界反兴奋剂条例禁用物质清单的类固醇药物,或者是利用兴奋剂检测方法存在的不足为逃脱药检而专门设计的类固醇药物,其未来的主要趋势是制造现今例行的运动兴奋剂控制尿样筛选、检测中容易分解的类固醇兴奋剂;另一个重要的趋势是从现有商品流通渠道和世界反兴奋剂条例禁用物质清单之外寻找或直接开发合成代谢活性高的合成类固醇药物。

Objective：Investigate the characteristic of designer steroid and discuss its development directions. Methods： Literature review and theoretical analysis. Conclusion： The primaryorientation in designer steroid research is to find novel designer steroid undeteetable in present routine sports doping control tests,another major direction is to search in exist steroid for ones with high anabolie activity but neither marketed nor named on the prohibited list at present, or to find new ones.