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肝癌TACE治疗后发热影响因素分析 被引量:17

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摘要 目的探讨影响肝癌经导管肝动脉化疗栓塞(TACE)治疗后发热因素。方法回顾分析45例患者60例次肝癌经TACE治疗后发热情况,同时采用多元回归分析影响TACE后发热的影响因素。以术后发热天数为因变量,自变量即分析因素包括患者年龄、Okuda分期、肿瘤类型、有无腹水、碘油用量、是否加用栓塞剂、术前血清谷丙转氨酶、总胆红素、白蛋白、甲胎蛋白水平、红细胞数、白细胞数、血小板数、血浆凝血酶原时间、既往有无TAE史等15项。结果影响TACE治疗后发热的因素按标准化回归系数绝对值大小依次为碘油用量(P=0.005)、加用栓塞剂(P=0.019)、Okuda分期(P=0.037)、年龄(P=0.724)、肿瘤类型(P=0.989)。碘油用量在患者的发热中起最重要作用。结论碘油用量是导致TACE治疗后发热的首要因素,加用栓塞剂会加重发热,治疗前全身状态和肝脏的局部状态包括Okuda分期、患者年龄、肿瘤类型也是影响发热的因素。
出处 《南方医科大学学报》 CAS CSCD 北大核心 2007年第9期1417-1418,共2页 Journal of Southern Medical University
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