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高立体选择性合成环氧乙烷-2-膦酸酯的研究 被引量：1

Study on stereoselective synthesis of oxirane-2-phosphonates
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摘要 利用铑(Ⅱ)催化重氮苄基膦酸酯与芳香醛或酮化学专一地进行环氧化反应,高产率、高立体选择性地合成了顺式环氧乙烷-2-膦酸酯。反应历程是重氮化合物先与醛或酮形成羰基叶立德中间体,然后发生自身环化反应。产物经红外光谱1、H核磁共振谱、质谱和X射线衍射确定结构。 The epoxidation of diazobenzylphosphonate with aldehydes or ketone catalyzed by dirhodium（Ⅱ） complex stereospecifically gave the cis-oxiranes in good yield.The reaction pathway involves carbonyl ylide intermediate in situ generated from diazo compound,which undergoes intramolecular ring closure to give epoxide-2-phosphonate.The products were determined through IR,^1H NMR,MS and X-ray single crystal diffraction.
作者 李志成 魏宏亮
机构地区 河南工业大学化学化工学院
出处 《化学研究与应用》 CAS CSCD 北大核心 2007年第9期1003-1006,共4页 Chemical Research and Application
基金 国家自然科学基金(20328203)资助项目 河南工业大学博士启动基金项目(150213)
关键词 环氧乙烷-2-膦酸酯 立体选择性 重氮苄基膦酸酯 芳香醛 cis-oxirane-2-phosphonate stereoselective α-diazobenzylphosphonate aldehyde
分类号 O623.624 [理学—有机化学]
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参考文献8

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同被引文献13

  • 1袁利萍,尹笃林,游奎一.D-72磺酸树脂催化合成(±)2-苯基-2-烷氧基乙醇[J].合成化学,2006,14(2):181-183. 被引量：4
  • 2尹笃林,徐琼,毛丽秋,等.可再生植物原料制备固体磺酸的方法[P].CN:ZL200610032187.9,2008-10-01.
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化学研究与应用
2007年 第9期

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