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FcγRⅡb调控浆细胞的存活和凋亡 被引量:1

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摘要 大部分血清中的免疫球蛋白是由骨髓浆细胞产生的。血清免疫球蛋白是维持体液免疫极其重要的物质,调控其数量和特异性对于抗感染免疫和预防自身免疫性疾病具有重要医学意义。
作者 王勇
出处 《国际免疫学杂志》 CAS 2007年第5期357-358,共2页 International Journal of Immunology
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  • 1莫毅,王伟,梁方方,兰干球,郭亚芬,蒋和生.双磷酸化His-PZR蛋白的表达与分离纯化[J].免疫学杂志,2009(1):94-96. 被引量:1
  • 2Cohen Solal JF, Cassard L, Fridman WH, etal. Fc gamma receptors[J]. Immunol Lett, 2004, 92(3): 199-205.
  • 3Reefman E, Dijstelbloem HM, Limburg PC, et al. Fc gamma receptors in the initiation and progression of systemic lupus erythematosus[J]. Immunol Cell Biol, 2003, 81(5): 382-389.
  • 4Takai T. Fc receptors and their role in immune regulation and autoimmunity[J]. Clin Exp Immunol, 2005, 25(1): 1-18.
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  • 6Sohn HW, Pierce SK, Tzeng SJ. Live cell imaging reveals that the inhibitory Fc gamma RIIB destabilizes B cell receptor membrane-lipid interactions and blocks immune synapse formation[J]. J Immunol, 2008, 180(2): 793-799.
  • 7Blank MC, Stefanescu RN, Masuda E, et al. Decreased transcription of the human FCGR2B gene mediated by the -343 G/C promoter polymorphism and association with systemic lupus erythematosus[J]. Hum Genet, 2005, 117(2/3): 220-227.
  • 8Stefanescu RN, Olferiev M, Liu Y, et al. Inhibitory Fe gamma receptors: from gene to disease [J]. Clin Exp Immunol, 2004, 24(4): 315-326.
  • 9Kalergis AM, Ravetch JV. Inducing tumor immunity through the selective engagement of activating Fc gamma receptors on dendritic cells[J]. J Exp Med, 2002, 195(12): 1653-1659.
  • 10Dhodapkar KM, Banerjee D, Connolly J, et al. Selective blockade of the inhibitory Fc receptor (Fe'yRIIB) in human dendritic cells and monocytes induces a type I interferon response program[J]. J Exp Med, 2007, 204(6): 1359-1369.

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