413例慢性肾功能衰竭的病因分析

Etiological analysis of 413 cases with chronic renal failure

目的了解慢性肾功能衰竭的常见病因,为指导防治慢性肾功能衰竭提供依据。方法回顾分析413例住院慢性肾功能衰竭的临床资料。结果413例慢性肾功能衰竭患者中因原发性肾小球疾病引起者占首位,共145例(35.1%);其次为糖尿病肾病,共107例(25.9%);高血压肾病78例(18.9%);梗阻性肾病44例(10.7%);慢性肾盂肾炎8例(1.9%);先天遗传性肾病6例(1.5%);狼疮性肾炎、乙肝相关性肾病等25例(6.1%)。结论慢性肾功能衰竭病因的构成比例与现有的文献资料有差异,糖尿病肾病,高血压肾病明显上升。梗阻性肾病在海南地区发病率明显高于内地。

Objective To understand the common causes of chronic renal failure （CRF） and the constituent ratio. Methods 413 cases with and CRF admitted in the past five years were analyzed. Results There were 145 cases with glomerulonephritis （35. 1% ）, 107 cases with diabetic nephropathies （25.9%）, 78 cases with hyportension - related nephropathy （ 18.9% ）, 44 cases with chronic obstructive nephropathy （ 10.7 % ）, 8 cases with chronic pyelonephritis （ 1.9 % ）, 6 cases with hereditary nephritis （ 1.5 % ）, 25 cases with lupus nephritis and hepatitis B - related renal disease （6.1% ）. Conclusion Glomerulonephritis is the most common cause of CRF （35.1% ）, Diabetic nephropathies is the second cause of CRF （25.69 % ） and Hyportension - related nephropathy is the third cause. There is signifcant difference in constituent ratio in CRF in this analysis comparing to that of the literatures.