耐甲氧西林金黄色葡萄球菌医院感染及耐药性分析

Survey of nosocomial infection of meticillin-resistant Staphylococcus aureus in Department of Neurosurgery

目的了解神经外科耐甲氧西林金黄色葡萄球菌（MRSA）医院感染情况，探讨医院感染防控措施。方法对惠州市中心人民医院神经外科2003年1月～2006年12月发生MRSA医院感染病例的有关资料进行回顾性调查分析。结果135例金黄色葡萄球菌感染者中，111例为MRSA感染，占82，2％；感染部位以下呼吸道为主，占92．79％；MRSA感染者病死率达14．41％。药敏结果显示MRSA除对万古霉素、利福平相对敏感外，对其它抗菌药物均有较强耐药性。结论严密监控神经外科MRSA感染，严格执行消毒隔离措施，降低下呼吸道感染发病率，对降低病死率有重要作用。

Objective To analyze the condition of nosocomial infection of MRSA in neurosurgery and to explore the control measures. Methods Retrospective analysis nosocomial infection with MRSA in patients who were admitted into the department of Neurosurgery during the period from Jan 2003 to Dec 2006 was made. Results A total of 135 Staphylococcus aureus infections were found. 111 isolates were methicillin - resistant Staphylococcus aureus （MRSA） with a detection rate of MRSA of 82.2 % . The infection sites were mainly in lower respiratory tract （92.79 % ）, 64 cases were complicated with other infections. The dead rate of MRSA was 14.41% .The rate of MRSA isolates resistant to used antibiotics was high except vancomycin, rifampin. Conclusion Effective measures De taken to monitor the resistant staus of MRSA to antibiotics and treat MRSA infection in Neurosurgery.