自体黑素细胞体外培养与移植治疗白癜风的研究

The Research on Autologous Melanocyte Culture in vitro and Transplantation for the Treatment of Vitiligo

【目的】研究和探索黑素细胞培养移植治疗白癜风的方法与疗效。【方法】采用从发疱壁上获取黑素细胞、纯黑素细胞培养与增殖、移植区刮除种植法,进行自体黑素细胞培养移植治疗白癜风。【结果】18例白癜风患者中21块皮损进行了自体黑素细胞培养移植,总有效率为90.48%。【结论】此操作方法较简单、治疗面积大,色素分部均匀,值得临床推广和应用。

To further investigate and explore the method and efficacy of the autologous melanocyte culture and transplantation for the treatment in vitiligo. [Methods]We obtained melanocytes from suction blister wall, cultivated and proliferated them, scratched vitiliginous area and transplantated melanocytes for the treatment of vitiligo. [Results]The 21 pieces of lesions of 18 patients were transplanted by autologous melanocytes. The total effective rate attached 90.48%. [Conclusion] This method of treatment in vitiligo by autologous melanocytes culture and transplantation is relatively simple operation, getting more treatment area, and excellent repigmentation. It is valuable in clinical application.