健脾疏肝汤治疗肠道易激综合征的临床和实验研究

Clinical and Experimental Studies on Bowel Irritable Syndrome Treated by Invigorating the Spleen and Dispersing the Stagnated Liver-Energy Decoction

采用健脾疏肝汤治疗了46例肠道易激综合征患者，临床总有效率达93．5％，与对照组比较P＜0．05。并通过实验表明健脾疏肝汤对胃肠功能有良好的双向调节作用，即降低小鼠小肠碳末推进百分率，抑制肌注新斯的明的小鼠胃肠推进运动的加快，也能抑制离体小肠的自发活动，对乙酰胆碱、氯化钡所致的肠管收缩有明显的拮抗作用，且可改善微循环和血液流变学指标，从而使失常的肠管运动机能趋向正常化。

46 cases with bowel irritable syndrome were treated by invigorating the spleen anddispersing the stagnated liver-energy decoction. The general clinical effective rate was 93. 5 % (P＜0. 05 ). The experimental study manifested that the decoction has the diphasic regulating actionfor gastrointestinal function. At the same time, the decoction can improve the microcirculation andindex of blood rheology.