先天性心脏病再次手术中应用抑肽酶减少术后出血的探讨

High dose Aprotinin in Reduction of Blood Loss during Reoperation on Congenital Heart Disease

报告２７例先天性心脏病再次手术患者体外循环中应用抑肽酶。结果显示：停转流后手术创面比较干燥，无渗血不止现象。除２例外，均未用纤维蛋白原类制剂或血小板，术后３小时纵隔引流量７７．８±５７．１ｍｌ，术后２４小时总引流量２０５±１４．３ｍｌ。结论：再次手术体外循环中使用抑肽酶术后出血量均较过去不用抑肽酶时明显减少。

Aprotinin was used in 27 pediatric cases of repeated open heart surgery. After cardiopulmonary bypass, the operative field was kept much drier without oozing of blood. Except 2 cases, no fibrinogen components and platelet were needed. The amount of mediastinal drainage of blood hours after operation was 77.8±51.1ml and the total amount 24 hours after operation was 205±14.3ml. Either the blood lost or the blood administered was less than those without administrating apportion.