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叶酸、亚甲基四氢叶酸还原酶基因多态性与白血病的研究进展

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摘要 亚甲基四氢叶酸还原酶是叶酸代谢途径中的关键酶，其常见的两个突变基因型使其编码的酶功能活性显著降低，从而影响叶酸的生物转化和功能。本文就叶酸代谢、MTHFR基因多态性与白血病易感性及其临床意义综述如下。
作者 张静（综述） 魏影非（审校）
机构地区 河北医科大学第三医院血液科
出处 《国际输血及血液学杂志》 CAS 2007年第5期429-433,共5页 International Journal of Blood Transfusion and Hematology
关键词 叶酸代谢 亚甲基四氢叶酸还原酶 基因多态性 白血病
分类号 R587.2 [医药卫生—内分泌]
  • 相关文献

参考文献50

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二级参考文献20

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国际输血及血液学杂志
2007年 第5期

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